Aerius tablets contain Desloratadine 5mg and the following inactive
ingredients:
Core: calcium hydrogen phosphate, microcrystalline cellulose, maize starch
and talc.
Coating: Opadry Blue, Opadry Clear, carnauba wax and white beeswax.
Drug Class And Mechanism: Desloratadine is an oral, long-acting
antihistamine that is similar chemically to loratadine (Claritin). It is
used to treat the symptoms caused by histamine. Histamine is a chemical
that is responsible for many of the signs and symptoms of allergic
reactions, for example, swelling of the lining of the nose, sneezing, and
itchy eyes. Histamine is released from histamine-storing cells (mast
cells) and then attaches to other cells that have receptors for histamine.
The attachment of the histamine to the receptors causes the cell to be
"activated," releasing other chemicals which produce the effects that we
associate with allergy. Desloratadine blocks one type of receptor for
histamine (the H1 receptor) and thus prevents activation of H1
receptor-containing cells by histamine. Desloratadine does not readily
enter the brain from the blood and, therefore, causes less drowsiness
(sedation). It is a member of a small family of non-sedating
antihistamines which includes loratadine (Claritin), cetirizine (Zyrtec),
and azelastine (Astelin). Desloratadine was approved by the FDA in
December, 2001.
Prescribed For: Desloratadine is used for the treatment of allergies and
chronic urticaria (hives) in adults and children 12 years of age or older.
Dosing: The recommended dose for adults and children 12 years or older is
5 mg daily. Syrup can be used for children two years and older with the
dose dependent on the age of the child. Desloratadine can be taken with or
without food.
Storage: Store at room temperature in tight, light resistant container.
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